| Jornada 1 | 28-08-2005 | VALLADOLID | 1 | MURCIA | 0 |
| Jornada 2 | 04-09-2005 | ALBACETE | 2 | VALLADOLID | 3 |
| Jornada 3 | 11-09-2005 | VALLADOLID | 0 | GIMNASTIC | 2 |
| Jornada 4 | 18-09-2005 | RECREATIVO | 2 | VALLADOLID | 0 |
| Jornada 5 | 25-09-2005 | VALLADOLID | 1 | MALAGA B | 1 |
| Jornada 6 | 02-10-2005 | REAL MADRID B | 2 | VALLADOLID | 3 |
| Jornada 7 | 09-10-2005 | VALLADOLID | 1 | ALMERIA | 0 |
| Jornada 8 | 16-10-2005 | CASTELLON | 0 | VALLADOLID | 0 |
| Jornada 9 | 23-10-2005 | VALLADOLID | 3 | NUMANCIA | 1 |
| Jornada 10 | 30-10-2005 | XEREZ | 0 | VALLADOLID | 0 |
| Jornada 11 | 06-11-2005 | VALLADOLID | 1 | HERCULES | 1 |
| Jornada 12 | 13-11-2005 | CIUDAD MURCIA | 0 | VALLADOLID | 2 |
| Jornada 13 | 20-11-2005 | VALLADOLID | 1 | TENERIFE | 1 |
| Jornada 14 | 27-11-2005 | SPORTING GIJON | 1 | VALLADOLID | 1 |
| Jornada 15 | 04-12-2005 | LLEIDA | 0 | VALLADOLID | 4 |
| Jornada 16 | 11-12-2005 | VALLADOLID | 0 | EIBAR | 0 |
| Jornada 17 | 18-12-2005 | LORCA | 2 | VALLADOLID | 0 |
| Jornada 18 | 21-12-2005 | VALLADOLID | 3 | LEVANTE | 3 |
| Jornada 19 | 08-01-2006 | POLI.EJIDO | 1 | VALLADOLID | 1 |
| Jornada 20 | 15-01-2006 | VALLADOLID | 3 | RAC.FERROL | 3 |
| Jornada 21 | 22-01-2006 | ELCHE | 0 | VALLADOLID | 2 |
| Jornada 22 | 29-01-2006 | MURCIA | 2 | VALLADOLID | 2 |
| Jornada 23 | 05-02-2006 | VALLADOLID | 0 | ALBACETE | 1 |
| Jornada 24 | 12-02-2006 | GIMNASTIC | 3 | VALLADOLID | 2 |
| Jornada 25 | 19-02-2006 | VALLADOLID | 0 | RECREATIVO | 1 |
| Jornada 26 | 26-02-2006 | MALAGA B | 2 | VALLADOLID | 1 |
| Jornada 27 | 05-03-2006 | VALLADOLID | 1 | REAL MADRID B | 0 |
| Jornada 28 | 12-03-2006 | ALMERIA | 2 | VALLADOLID | 1 |
| Jornada 29 | 19-03-2006 | VALLADOLID | 1 | CASTELLON | 0 |
| Jornada 30 | 26-03-2006 | NUMANCIA | 3 | VALLADOLID | 2 |
| Jornada 31 | 02-04-2006 | VALLADOLID | 3 | XEREZ | 1 |
| Jornada 32 | 09-04-2006 | HERCULES | 2 | VALLADOLID | 0 |
| Jornada 33 | 16-04-2006 | VALLADOLID | 0 | CIUDAD MURCIA | 2 |
| Jornada 34 | 23-04-2006 | TENERIFE | 2 | VALLADOLID | 1 |
| Jornada 35 | 30-04-2006 | VALLADOLID | 1 | SPORTING GIJON | 3 |
| Jornada 36 | 07-05-2006 | VALLADOLID | 3 | LLEIDA | 2 |
| Jornada 37 | 14-05-2006 | EIBAR | 0 | VALLADOLID | 1 |
| Jornada 38 | 21-05-2006 | VALLADOLID | 1 | LORCA | 1 |
| Jornada 39 | 28-05-2006 | LEVANTE | 2 | VALLADOLID | 1 |
| Jornada 40 | 04-06-2006 | VALLADOLID | 0 | POLI.EJIDO | 1 |
| Jornada 41 | 11-06-2006 | RAC.FERROL | 0 | VALLADOLID | 1 |
| Jornada 42 | 18-06-2006 | VALLADOLID | 2 | ELCHE | 2 |